The value of the pK a changes with temperature and can be understood qualitatively based on Le Châteliers principle. The acid dissociation constant for an acid is a direct consequence of the underlying thermodynamics of the dissociation reaction. 1 The pK a value is directly proportional to the standard Gibbs free energy change for the reaction. . Covalent compounds have weak force of attraction between their molecules so they are usually liquids or gases. In the early 1960s however it was found that relatively mild ionic detergents such as deoxycholate can solubilize selected components of the inner mitochondrial membrane in their native form. C Ionic compounds conduct electricity when dissolved in water or when melted because they contain ions charged particles. Information for New Authors. Acids are typically ionic with a positive hydrogen ion attached to a negative anion. What are acids base and salt.